我们关注豆科植物苜蓿响应营养胁迫、响应酸铝胁迫、共生固氮的分子机理。克隆了植物抗酸铝负调控基因RAE1等,授权专利1项,研究成果发表在PNAS等学术期刊。
每年可招硕士研究生2名,欢迎有兴趣的同学报考。
主持项目:
1. 转录因子MtSTOP1调控蒺藜苜蓿抗铝毒功能研究,2022-1至2024-12,国家自然科学基金青年项目。
2. 苜蓿抗铝毒机制研究,2020-8至2025-7,中央高校基本科研业务费。
3. 蒺藜苜蓿抗铝毒转录因子转录后调控机制研究,2022-1至2022-12,中央高校基本科研业务费。
学术论文:
10. Jin D#, Chen J, Kang Y, Yang F, Yu D, Liu X, Yan C, Guo Z*, Zhang Y* (2024). Genome-wide characterization, transcriptome profiling, and functional analysis of the ALMT gene family in Medicago for aluminum resistance. J Plant Physiol 297:154262. (5-Year IF2023 = 4.1)通讯作者
9. Wei X#, Zhu Y#, Xie W, Ren W, Zhang Y, Zhang H, Dai S, Huang CF* (2024). H2O2 negatively regulates aluminum resistance via oxidation and degradation of the transcription factor STOP1. Plant Cell 36:688-708. (5-Year IF2023 = 11.1)参与作者
8. Zhu YF#, Guo J#, Zhang Y, Huang CF* (2021). The THO/TREX Complex Component RAE2/TEX1 Is Involved in the Regulation of Aluminum Resistance and Low Phosphate Response in Arabidopsis. Front Plant Sci 12:698443.(5-Year IF2023 = 5.3)参与作者
7. Fang Q#, Zhou F#, Zhang Y, Singh S, Huang CF* (2021). Degradation of STOP1 mediated by the F-box proteins RAH1 and RAE1 balances aluminum resistance and plant growth in Arabidopsis thaliana. Plant J 106:493-506.(5-Year IF2023 = 7.1)参与作者
6. Fang Q#, Zhang J#, Zhang Y, Fan N, van den Burg HA, Huang CF* (2020). Regulation of Aluminum Resistance in Arabidopsis Involves the SUMOylation of the Zinc Finger Transcription Factor STOP1. Plant Cell 32:3921-3938.(5-Year IF2023 = 11.1)参与作者
5. Guo J#, Zhang Y, Gao H, Li S, Wang ZY, Huang CF* (2020) Mutation of HPR1 encoding a component of the THO/TREX complex reduces STOP1 accumulation and aluminium resistance in Arabidopsis thaliana. New Phytol 228:179-193.(5-Year IF2023 = 10.2)参与作者
4. Yin X#, Bi R#, Ma P#, Zhang S#, Zhang Y, Sun Y, Zhang Y, Jing Y, Yu M, Wang W*, Tan L*, Di W*, Zhuang G*, Cai MC* (2020). Multiregion whole-genome sequencing depicts intratumour heterogeneity and punctuated evolution in ovarian clear cell carcinoma. J Med Genet 57:605-609.(5-Year IF2023 = 4.1)参与作者
3. Yang CH#, Zhang Y#, Huang CF* (2019) Reduction in cadmium accumulation in japonica rice grains by CRISPR/Cas9-mediated editing of OsNRAMP5. J Integr Agric 18:688-697.(5-Year IF2023 = 4.5)共同第一作者
2. Zhang Y#, Zhang J#, Guo J#, Zhou F, Singh S, Xu X, Xie Q, Yang Z, Huang CF* (2019) F-box protein RAE1 regulates the stability of the aluminum-resistance transcription factor STOP1 in Arabidopsis. Proc Natl Acad Sci U S A 116:319-327.(5-Year IF2023 = 10.8)第一作者
1. Zhang Y#, Guo J#, Chen M, Li L, Wang L, Huang CF* (2018) The cell cycle checkpoint regulator ATR is required for internal aluminum toxicity-mediated root growth inhibition in Arabidopsis. Front Plant Sci 9:118. (5-Year IF2023 = 5.3)第一作者