主要研究方向:微生物生理生化及微生物酶学,包括微生物体内重要代谢反应及催化酶类的结构和功能的研究,如灵菌红素及PQQ合成及调节的研究;微生物响应不良环境的机制研究;微生物胞外酶结构和功能的研究。
中科院上海植物生理生态研究所 微生物学 With Certificate of Graduation for Doctorate Study Doctoral Degree in Science
南京农业大学资环院 微生物学 With Certificate of Graduation for Study as Master's Candidates Master's Degree in Science
南京农业大学土化系 微生物学 University graduated Bachelor's Degree in Science
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南京农业大学生命科学学院教师
微生物胞外酶结构和功能的研究、微生物响应不良环境的机制研究、微生物生理生化及微生物酶学
Liu Xia,Xu Dongqing,Wu Defeng,Xu Mengxue,Wang Ying,Wang Weiwu,Ran Tingting.BarA/UvrY differentially regulates prodigiosin biosynthesis and swarming motility in Serratia marcescens FS14,RESEARCH IN MICROBIOLOGY,2023,174(3)(Participating authors)
Zhao Xuezheng,Xu Dongqing,Xia Wenxiao,Hu Menghua,Peng Xuede,Liu Xia,Ran Tingting,Wang Weiwu.Multicopy expression of sigma factor RpoH reduces prodigiosin biosynthesis in Serratia marcescens FS14,ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY,2023,116(11):1197-1208(Participating authors)
Xu Mengxue,Liu Xia,Li Xiaoyan,Chen Lin,Li Shengzhe,Sun Bo,Xu Dongqing,Ran Tingting,Wang Weiwu.Crystal structure of prodigiosin binding protein PgbP, a GNAT family protein, in Serratia marcescens FS14,BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2023,640:73-79(Participating authors)
Xu Mengxue,Xu Dongqing,Gao Mengxiao,Zhuang Xuebo,Wang Weiwu,Sun Bo,Ran Tingting.Structural basis for substrate binding and catalytic mechanism of the key enzyme VioD in the violacein synthesis pathway,PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS,2023,91(7):956-966(Participating authors)
Qiu Shenshen,Xu Dongqing,Xu Mengxue,Zhou Huan,Sun Ning,Zhang Li,Zhao Mengmeng,He Jianhua,Ran Tingting,Sun Bo,Wang Weiwu.Crystal structures of PigF, an O-methyltransferase involved in the prodigiosin synthetic pathway, reveal an induced-fit substrate-recognition mechanism,IUCRJ,2022,9:316-327(Participating authors)
Xu Mengxue,Xu Qin,Wang Meitian,Qiu Shenshen,Xu Dongqing,Zhang Weizhe,Wang Weiwu,He Jianhua,Wang Qisheng,Ran Tingting,Sun Bo.Crystal structures of TTHA1265 and TTHA1264/TTHA1265 complex reveal an intrinsic heterodimeric assembly,INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2022,207:424-433(Participating authors)