王春明

Professor    Supervisor of Doctorate Candidates

  • School/Department: College of Agriculture
  • Education Level:With Certificate of Graduation for Doctorate Study
  • Degree:Doctoral Degree in Agriculture
  • Professional Title:Professor
  • Alma Mater:南京农业大学
  • Personal Profile

先后任日本九州大学农学部研究员,新加坡国立大学淡马锡生命科学研究院博士后(Postdoctoral Fellow)、研究员(Research Fellow)和高级研究员(Manager)。曾赴美国、日本、瑞士、新加坡和印度尼西亚等国家进行学术交流和合作研究,从事水稻等作物的遗传改良和基因组选择研究。20126月南京农业大学引进人才任教授,博士生导师。2012年入选江苏省高层次引进人才双创教授。

研究兴趣:植物在非生物胁迫下能够感知和适应变化的环境,并进化成复杂的耐逆机制,如耐低氮和耐盐碱等重要农艺性状是多基因控制的数量性状。我们在植物耐逆遗传育种学科领域,通过整合数量遗传学、表观遗传学、基因组学、代谢组学、生物信息学和分子生物学等学科的理论和方法,研究水稻耐低氮耐盐碱的遗传变异和选择驯化,在基因组学和代谢组学层面阐明关键基因调控网络及其分子机制,逐步破译植物氮高效和耐盐碱性状的遗传规律。同时研究硝态氮、铵态氮、有机氮以及盐碱胁迫对作物农艺性状形成的作用机制。上述研究不仅在植物遗传育种和植物营养的交叉学科理论体系具有科学意义,对水稻双增双减(增产增效和减肥减药)的基因组育种和作物生产具有应用价值。

学生培养:获南京农业大学校长奖学金1名,江苏省优秀博士学位论文奖1名,中国作物学会优秀博士论文奖1名,博士生国家奖学金1名,硕士生国家奖学金1名。

论文项目:SCI论文100余篇,其中以通讯作者在Nature Genetics (2024), Nature Communications (2019, 2023)等杂志发表SCI文章发表35篇。以通讯作者撰写英文研究专著一章(Book Chapter)。以副主编出版《耐盐碱水稻遗传和栽培学》专著。先后主持国家863计划项目和国家重点研发计划课题2项,主持国家自然科学基金面上项目4项。

代表性工作成果:

1.        研究水稻氮高效关键基因及其调控网络,对于培育氮高效水稻品种具有重要科学意义和应用价值。成果主要内容:连续三年进行大规模的田间表型鉴定和全基因组关联分析,克隆了氮素吸收转运分子模块OsGATA8-OsAMT3.2, OsGATA8-OsTCP19, OsNAC42-OsNPF6.1和同化模块OsNLP4-OsNiR 鉴定了与氮利用效率相关的籽粒发育基因OsGS1;1,揭示了水稻氮同化基因GS1;1自然变异和促进籽粒发育分子机制。创新点:优异单倍型和电生理分析阐明了OsNPF6.1OsNiR启动子元件遗传变异及转录激活稳定性;高活性转录本OsGS1;1b过表达可提高NUE。成效:解析了氮高效分子模块的调控机制,为减少氮肥施用量和农业可持续发展提出育种途径。国际著名期刊发表了相关研究成果(Nature Genetics, 2024 DOI: 10.1038/s41588-024-01795-7; Nature Communications, 2019 10, 5279Plant Biotechnology Journal, 2021, 19, 167-176Plant Journal, 2022, DOI: 10.1111/tpj.15768)。

2.        植物盐害包括离子胁迫、渗透胁迫、氧化胁迫和养分不平衡,是多基因控制的复杂性状。成果主要内容:通过对水稻地方品种进行全基因组关联分析,确定了10个耐盐候选基因。创新点:编码转录因子OsWRKY53和丝裂原活化蛋白激酶激酶OsMKK10.2介导根Na+流。OsWRKY53作为负调节因子调节OsMKK10.2的表达,促进离子稳态。阐明了微管蛋白在盐胁迫中稳定离子平衡的作用机制,发现OsTUB1/OsKinesin13A在盐胁迫下可以稳定钠离子转运蛋白OsHKT1;5,保护水稻免受盐胁迫毒害。此外,TSV编码质体氧化还原酶,影响低温或氧化胁迫反应。成效:揭示了水稻通过OsWRKY53-OsMKK10.2OsWRKY53-OsHKT1;5OsTUB1/OsKinesin13A模块协调防御盐胁迫等分子机制。国际著名期刊发表了相关研究新进展(Nature Communications, 2023, 143550; Plant Biotechnology Journal, 2024 doi: 10.1111/pbi.14419New Phytologist 2022 doi:10.1111/nph.18282New Phytologist, 2017, DOI:10.1111/nph.14482)

 

近五年通讯作者论文 (*: 通讯作者)

1.          Wei Wu#, Xiaoou Dong#, Gaoming Chen, Zhixi Lin, Wenchao Chi, Weijie Tang, Jun Yu, Saisai Wang, Xingzhou Jiang, Xiaolan Liu, Yujun Wu, Chunyuan Wang, Xinran Cheng, Wei Zhang, Wei Xuan, William Terzaghi, Pamela C. Ronald, Haiyang Wang, Chunming Wang*, & Jianmin Wan*, The elite haplotype OsGATA8-H confers yield increase by coordinating nitrogen uptake and productive tiller formation in rice Nature Genetics, (2024). DOI10.1038/s41588-024-01795-7

2.          Jun Yu #, Chengsong Zhu #, Wei Xuan #, Hongzhou An #, Yunlu Tian, Baoxiang Wang, Wenchao Chi, Gaoming Chen, Yuwei Ge, Jin Li, Zhaoyang Dai, Yan Liu, Zhiguang Sun, Dayong Xu, Chunming Wang* & Jianmin Wan* Genome-wide association studies identify OsWRKY53 as a key regulator of salt tolerance in rice Nature Communications, (2023) 143550 DOI10.1038/s41467-023-39167-0

3.          Weijie Tang#, Jian Ye#, Xiangmei Yao#, Pingzhi Zhao, Wei Xuan, Yunlu Tian, Yuanyan Zhang, Shuang Xu, Hongzhou An, Gaoming Chen, Jun Yu, Wei Wu, Yuwei Ge, Xiaolan Liu, Jin Li, Hanzhi Zhang, Yaqin Zhao, Bing Yang, Xingzhou Jiang, Chao Peng, Cong Zhou, William Terzaghi, Chunming Wang* & Jianmin Wan* Genome-wide associated study identifies NAC42-activated nitrate transporter conferring high nitrogen use efficiency in rice. Nature Communications, (2019) Nov 21;10(1):5279

4.          Yuwei Ge #, Gaoming Chen #, Xinran Cheng #, Chao Li, Yunlu Tian, Wenchao Chi, Jin Li, Zhaoyang Dai, Chunyuan Wang, Erchao Duan, Yan Liu, Zhiguang Sun, Jingfang Li, Baoxiang Wang, Dayong XuXianjun Sun, Hui Zhang, Wenhua Zhang, Chunming Wang*, and Jianmin Wan*,The superior allele LEA12OR in wild rice enhances salt tolerance and yield Plant Biotechnology Journal, 2024, doi: 10.1111/pbi.14419

5.          Gaoming Chen#, Wei Xuan#, Pingzhi Zhao#, Xiangmei Yao, Chao Peng, Yunlu Tian, Jian Ye, Baoxiang Wang, Jun He, Wenchao Chi, Jun Yu, Yuwei Ge, Jin Li, Zhaoyang Dai, Dayong Xu, Chunming Wang*, Jianmin Wan*, OsTUB1 confers salt-insensitivity by interacting with Kinesin13A to stabilize microtubule and ion transporter in rice New Phytologist, doi:2022 10.1111/nph.18282

6.          Xiaolan Liu#, Yunlu Tian#, Wenchao Chi, Hanzhi Zhang, Jun Yu, Gaoming Chen, Wei Wu, Xingzhou Jiang, Saisai Wang, Zhixi Lin, Wei Xuan, Jian Ye, Baoxiang Wang, Yan Liu, Zhiguang Sun, Dayong Xu, Chunming Wang*, Jianmin Wan* Alternative splicing of OsGS1;1 affects nitrogen-use efficiency, grain development, and amylose content in rice Plant Journal, 2022, doi: 10.1111/tpj.15768

7.          Jun Yu#, Wei Xuan#, Yunlu Tian, Lei Fan, Juan Sun, Weijie Tang, Gaoming Chen, Baoxiang Wang, Yan Liu, Wei Wu, Xiaolan Liu, Xingzhou Jiang, Cong Zhou, Zhaoyang Dai, Dayong Xu, Chunming Wang*, Jianmin Wan* Enhanced OsNLP4-OsNiR cascade confers nitrogen use efficiency by promoting tiller number in rice Plant Biotechnology Journal, 2021, 19, 167-176

8.          Juan Sun, Tianhui Zheng, Jun Yu, Tingting Wu, Xinhua Wang, Gaoming Chen, Yunlu Tian, Huan Zhang, Yihua Wang, William Terzaghi, Chunming Wang*, Jianmin Wan* TSV, a putative plastidic oxidoreductase, protects rice chloroplasts from cold stress during development by interacting with plastidic Thioredoxin Z. New Phytologist, 2017, DOI:10.1111/nph.14482

9.          Tianzi Lin#, Cong Zhou#, Gaoming Chen, Jun Yu, Wei Wu, Yuwei Ge, Xiaolan Liu, Jin Li, Xingzhou Jiang, Weijie Tang, Yunlu Tian, Zhigang Zhao, Chengsong Zhu, Chunming Wang* & Jianmin Wan* Heterosis-associated genes confer high yield in super hybrid rice Theoretical and Applied Genetics, 2020, 133, 3287–3297

10.       Hongzhou An, Kai Liu, Baoxiang Wang, Yunlu Tian, Yuwei Ge, Yuanyan Zhang, Weijie Tang, Gaoming Chen, Jun Yu, Wei Wu, Xiaolan Liu, Yaqin Zhao, Jin Li, Hanzhi Zhang, Bing Yang, Xingzhou Jiang, Chao Peng, Cong Zhou, Chengsong Zhu, Chunming Wang* & Jianmin Wan* Genome-wide association study identifies QTLs conferring salt tolerance in rice. Plant Breeding, 2020, 139: 73-82

专著:

1.          以通讯作者撰写英文研究专著Compendium of Plant Genomes. Jatropha. Springer Science Publishers, New York. The Jatropha Genome 1: 199-219. 2017出版。DOI 10.1007/978-3-319-49653-5_2Hardcover ISBN 978-3-319-49651-1

2.          以副主编出版《耐盐碱水稻遗传和栽培学》袁隆平主编 山东科学技术出版社 20228月出版。

 

课程教学:

研究生课程《Biostatistics》(生物统计学全英文课程),植物遗传育种导论(全英文课程);

本科生课程《应用数量遗传》。


  • Educational Experience
  • scientific research awards
  • 南京农业大学   作物遗传育种   With Certificate of Graduation for Doctorate Study   Doctoral Degree in Agriculture

  • 南京农业大学   作物遗传育种   With Certificate of Graduation for Study as Master's Candidates   Master's Degree in Agriculture

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  • Work Experience
  • 南京农业大学农学院

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