教育及工作经历
教育背景
2012/09–2015/12 南京农业大学,微生物学,博士
2010/09–2012/06 南京农业大学,微生物学,硕士
2006/09–2010/06 南京农业大学,生物科学专业,学士
工作经历
2022/02–至今 南京农业大学,生命科学学院,副研究员
2018/02–2022/02 南京农业大学,生命科学学院,师资博士后,助理研究员
2016/08–2018/01 江苏省农业科学研究院,助理研究员
研究方向
甲烷氧化菌生理遗传与代谢工程
细菌代谢异源化合物的转录调控
合成生物学
联系方式
mc@njau.edu.cn
获奖与成果
学术获奖
1. 第十八次全国环境微生物学研讨会“简浩然环境微生物学基金”优秀论文奖 (2015)
2. 南京农业大学优秀博士学位论文 (2017)
主持科研项目(按级别排序)
1. 国家自然科学基金面上项目,32470103,50万,2025/01–2028/12,主持
2. 国家自然科学基金面上项目,32170126,58万,2022/01–2025/12,主持
3. 国家自然科学基金青年基金项目,31800095,25万,2019/01–2021/12,主持
4. 江苏省自然科学基金青年项目,BK20180541,20万,2018/07–2021/06,主持
5. 中国博士后基金面上项目,2018M642262,5万,2019/01–2020/12,主持
6. 江苏省博士后科研资助,2018K052B,5万,2018/09–2020/06,主持
7. 江苏省重点研发计划社会发展面上项目,BE2020692,50万,2020/09–2023/06,项目骨干
8. 中央高校基本科研业务费,KYCYXT2022003,30万,2022/01至2024/12,主持
9. 中央高校基本科研业务费,KJQN201940,10万,2019/01至2019/12,主持
10. 南京农业大学科研启动费,Z521911201,10万,2019/01至2021/12,主持
已发表学术论文(#共同第一作者;*通讯作者)
1. Cheng M, Pei D, He L, Fei Q, Yan X*. Cre/lox-mediated CRISPRi library reveals core genome of a type I methanotroph Methylotuvimicrobium buryatense 5GB1C.Applied and Environmental Microbiology. 2023, 89(1):e01883-22.
2. Cheng M#, Chen D#, Parales RE, Jiang J*. Oxygenases as powerful weapons in the microbial degradation of pesticides. Annual Review of Microbiology. 2022, 76:325-348.
3. Cheng M#, Qian Y#, Xing Z, Zylstra G, Huang X*. The low-nanomolar 4-nitrobenzoate-responsive repressor PnbX negatively regulates the actinomycete-derived 4-nitrobenzoate-degrading pnb locus. Environmental Microbiology. 2021, 23(11):7028-7041.
4. Cheng M, Pei D, He X, Liu Y, Zhu P, Yan X*. The operon encoding hydrolytic dehalogenation of 4-chlorobenzoate is transcriptionally regulated by the TetR-type repressor FcbR and its ligand 4-chlorobenzoyl coenzyme A. Applied and Environmental Microbiology. 2021, 87(6):e02652-20.
5. Cheng M, Meng Q, Yang Y, Chu C, Chen Q, Li Y, Cheng D, Hong Q, Yan X*, He J. The two-component monooxygenase MeaXY initiates the downstream pathway of chloroacetanilide herbicide catabolism in sphingomonads.Applied and Environmental Microbiology. 2017, 83(7):e03241-16. (Spotlight article)
6. Cheng M, Chen K, Guo S, Huang X, He J, Li S, Jiang J*. PbaR, an IclR family transcriptional activator for the regulation of the 3-phenoxybenzoate 1’,2’-dioxygenase gene cluster in Sphingobium wenxiniae JZ-1T. Applied and Environmental Microbiology. 2015, 81(23):8084-8092.
7. Cheng M, Xing Z, Lu L, Chen F, He J, Huang X*. A plasmid-based genomic screening system for transcriptional regulators of non-adjacent xenobiotic catabolism genes.Applied Microbiology and Biotechnology. 2020, 104(3):1163-1174.
8. Cheng M, Yan X, He J, Qiu J*, Chen Q. Comparative genome analysis reveals the evolution of chloroacetanilide herbicide mineralization in Sphingomonas wittichii DC-6.Archives of Microbiology. 2019, 201(7):907-918.
9. Cheng M, Li Y, Ma Y, Qiu J*, Yan X, He J. Complete genome sequence of Sphingobium baderi DE-13, an alkyl-substituted aniline-mineralizing bacterium. Current Microbiology. 2018, 75(1):27-31.
10. Cheng M, Zhang H, Zhang J, Hu G, Zhang J, He J, Huang X*. Lysinibacillus fluoroglycofenilyticus sp. nov., a bacterium isolated from fluoroglycofen contaminated soil. Antonie Van Leeuwenhoek International Journal of General and Molecular Microbiology. 2015, 107(1):157-164.
11. Shang N#, Chen L#, Cheng M#, Tian Y, Huang X*. Biodegradation of diphenyl ether herbicide lactofen by Bacillus sp. YS-1 and characterization of two initial degrading esterases. Science of the Total Environment. 2022, 806:151357.
12. Zhu P#, Cheng M#, Pei D, Liu Y, Yan X*. Methylomonas rhizoryzae sp. nov., a type I methanotroph isolated from the rhizosphere soil of rice. Antonie Van Leeuwenhoek International Journal of General and Molecular Microbiology. 2020, 113(12):2167-2176.
更新于2024年10月