成明根
个人信息
个人简介

教育及工作经历

教育背景

2012/09–2015/12 南京农业大学,微生物学,博士

2010/09–2012/06 南京农业大学,微生物学,硕士

2006/09–2010/06 南京农业大学,生物科学专业,学士

工作经历

2022/02–至今 南京农业大学,生命科学学院,副研究员

2018/02–2022/02 南京农业大学,生命科学学院,师资博士后,助理研究员

2016/08–2018/01 江苏省农业科学研究院,助理研究员

研究方向

甲烷氧化菌生理遗传与代谢工程

细菌代谢异源化合物的转录调控

合成生物学

联系方式

mc@njau.edu.cn

获奖与成果

学术获奖

1.        第十八次全国环境微生物学研讨会简浩然环境微生物学基金优秀论文奖 (2015)

2.        南京农业大学优秀博士学位论文 (2017)

主持科研项目(按级别排序)

1.        国家自然科学基金面上项目,3247010350万,2025/01–2028/12,主持

2.        国家自然科学基金面上项目,3217012658万,2022/01–2025/12,主持

3.        国家自然科学基金青年基金项目3180009525万,2019/01–2021/12,主持

4.        江苏省自然科学基金青年项目,BK2018054120万,2018/07–2021/06,主持

5.        中国博士后基金面上项目,2018M6422625万,2019/01–2020/12,主持

6.        江苏省博士后科研资助,2018K052B5万,2018/09–2020/06,主持

7.        江苏省重点研发计划社会发展面上项目,BE202069250万,2020/09–2023/06,项目骨干

8.        中央高校基本科研业务费,KYCYXT202200330万,2022/012024/12,主持

9.        中央高校基本科研业务费,KJQN20194010万,2019/012019/12,主持

10.        南京农业大学科研启动费,Z52191120110万,2019/012021/12,主持

已发表学术论文(#共同第一作者;*通讯作者)

1.        Cheng M, Pei D, He L, Fei Q, Yan X*. Cre/lox-mediated CRISPRi library reveals core genome of a type I methanotroph Methylotuvimicrobium buryatense 5GB1C.Applied and Environmental Microbiology. 2023, 89(1):e01883-22.

2.        Cheng M#, Chen D#, Parales RE, Jiang J*. Oxygenases as powerful weapons in the microbial degradation of pesticides. Annual Review of Microbiology. 2022, 76:325-348.

3.        Cheng M#, Qian Y#, Xing Z, Zylstra G, Huang X*. The low-nanomolar 4-nitrobenzoate-responsive repressor PnbX negatively regulates the actinomycete-derived 4-nitrobenzoate-degrading pnb locus. Environmental Microbiology. 2021, 23(11):7028-7041.

4.        Cheng M, Pei D, He X, Liu Y, Zhu P, Yan X*. The operon encoding hydrolytic dehalogenation of 4-chlorobenzoate is transcriptionally regulated by the TetR-type repressor FcbR and its ligand 4-chlorobenzoyl coenzyme A. Applied and Environmental Microbiology. 2021, 87(6):e02652-20.

5.        Cheng M, Meng Q, Yang Y, Chu C, Chen Q, Li Y, Cheng D, Hong Q, Yan X*, He J. The two-component monooxygenase MeaXY initiates the downstream pathway of chloroacetanilide herbicide catabolism in sphingomonads.Applied and Environmental Microbiology. 2017, 83(7):e03241-16. (Spotlight article)

6.        Cheng M, Chen K, Guo S, Huang X, He J, Li S, Jiang J*. PbaR, an IclR family transcriptional activator for the regulation of the 3-phenoxybenzoate 1’,2’-dioxygenase gene cluster in Sphingobium wenxiniae JZ-1T. Applied and Environmental Microbiology. 2015, 81(23):8084-8092.

7.        Cheng M, Xing Z, Lu L, Chen F, He J, Huang X*. A plasmid-based genomic screening system for transcriptional regulators of non-adjacent xenobiotic catabolism genes.Applied Microbiology and Biotechnology. 2020, 104(3):1163-1174.

8.        Cheng M, Yan X, He J, Qiu J*, Chen Q. Comparative genome analysis reveals the evolution of chloroacetanilide herbicide mineralization in Sphingomonas wittichii DC-6.Archives of Microbiology. 2019, 201(7):907-918.

9.        Cheng M, Li Y, Ma Y, Qiu J*, Yan X, He J. Complete genome sequence of Sphingobium baderi DE-13, an alkyl-substituted aniline-mineralizing bacterium. Current Microbiology. 2018, 75(1):27-31.

10.    Cheng M, Zhang H, Zhang J, Hu G, Zhang J, He J, Huang X*. Lysinibacillus fluoroglycofenilyticus sp. nov., a bacterium isolated from fluoroglycofen contaminated soil. Antonie Van Leeuwenhoek International Journal of General and Molecular Microbiology. 2015, 107(1):157-164.

11.    Shang N#, Chen L#, Cheng M#, Tian Y, Huang X*. Biodegradation of diphenyl ether herbicide lactofen by Bacillus sp. YS-1 and characterization of two initial degrading esterases. Science of the Total Environment. 2022, 806:151357.

12.    Zhu P#, Cheng M#, Pei D, Liu Y, Yan X*. Methylomonas rhizoryzae sp. nov., a type I methanotroph isolated from the rhizosphere soil of rice. Antonie Van Leeuwenhoek International Journal of General and Molecular Microbiology. 2020, 113(12):2167-2176.

 

更新于202410


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