南京农业大学“钟山学者”特聘教授。目前受聘为国务院学位委员会植物保护学科评议组成员、国家农业转基因生物安全委员会委员、农业农村部植物保护专家指导组成员、全国农业有害生物抗药性风险评估与对策专家组成员。目前担任Pest Management Science主编，Insect Biochemistr and Molecular Biology, Insect Science和Journal of Integrative Agriculture编委。

长期从事昆虫分子毒理和农业害虫抗药性研究，主持和承担国家自然科学基金、转基因生物品种培育重大科研专项、国家重点研发计划、行业科技专项等课题30多项。在Nature Biotechnology, PNAS, Nature Communications, PLoS Pathogens, PLoS Genetics, Molecular Ecology, Insect Biochemistry and Molecular Biology, Applied and Environmental Microbiology, Pest Management Science, Pesticide Biochemistry and Physiology等重要国际学术刊物发表SCI论文130余篇。       

获教育部科技进步奖二等奖1项（1999，第1完成人）、教育部自然科学奖二等奖1项（2006，第2完成人）、国家科学技术进步奖二等奖1项（2010，第3完成人）。先后获得教育部首届高校青年教师奖（1999）、江苏省第六届青年科技奖（2000）、江苏省"333高层次人才培养工程"首批中青年科技领军人才（2007）、“新世纪百千万人才工程”国家级人选（2009）、全国农业科研杰出人才（2015）。   

代表性论文：

1. Wang, X., Y. Yue, Y. Zhai, F. Wang, X. Zhuang, S. Wu, Y. Yang, B. E. Tabashnik and Y. Wu*. Functional redundancy in the toxic pathway of Bt protein Cry1Ab, but not Cry1Fa, against the Asian corn borer. PNAS, 2025, 122: e2503674122. 

2. Shi, Y., Q. Liu, W. Lu, J. Yuan, Y. Yang, J. Oakeshott and Y. Wu*. Divergent amplifications of CYP9A cytochrome P450 genes provide two noctuid pests with differential protection against xenobiotics. PNAS, 2023, 120: e2308685120.

3. Wang, H., Y. Shi, L. Wang, S. Liu, S. Wu, Y. Yang, R. Feyereisen and Y. Wu*. CYP6AE gene cluster knockout in Helicoverpa armigera reveals role in detoxification of phytochemicals and insecticides. Nature Communications, 2018, 9: 4820.

4. Jin, L., J. Wang, F. Guan, J. Zhang, S. Yu, S. Liu, Y. Xue, L. Li, S. Wu, X. Wang, Y. Yang, H. Abdelgaffar, J. L. Jurat-Fuentes, B. E. Tabashnik and Y. Wu*. Dominant point mutation in a tetraspanin gene associated with field-evolved resistance of cotton bollworm to transgenic Bt cotton. PNAS, 2018, 115: 11760-11765.

5. Jin, L., H. Zhang, Y. Lu, Y. Yang, K. Wu, B. E. Tabashnik and Y. Wu*. Large-scale test of the natural refuge strategy for delaying insect resistance to transgenic Bt crops. Nature Biotechnology, 2015, 33: 169-174.

6. Zhang, H., W. Tian, J. Zhao, L. Jin, J. Yang, C. Liu, Y. Yang, S. Wu, K. Wu, J. Cui, B. E. Tabashnik and Y. Wu*. Diverse genetic basis of field-evolved resistance to Bt cotton in cotton bollworm from China. PNAS, 2012, 109: 10275-10280.