男，工学博士，生命科学学院植物生物学系副教授，南京农业大学高层次引进人才。

联系方式：wuyou@njau.edu.cn

地址：南京农业大学生科楼B6017

Google Schoolar: ‪You Wu‬ - ‪Google Scholar‬

一. 研究方向：

1. RNA表观遗传修饰转录后调控功能解析

2. 多组学生物信息算法与软件开发

3. 人工智能挖掘关键性状标志物，赋能作物智能育种。

招生方向：

二. 受教育和工作经历：

2026/9 - 今   南京农业大学，生命科学学院，副教授

2021/5—2025/6  上海交通大学生命科学技术学院 遗传发育系 博士后 

2013/9—2021/6  上海交通大学 机器人研究所 博士

2009/9—2013/9  哈尔滨工业大学 机械设计制造及其自动化 本科

教学情况

主讲本科生课程《文献检索与科技论文写作》

科研情况

一. 主要科研项目

1. 国家自然科学基金青年基金项目 2020 - 2022（主持）

2. 上海市自然科学基金 2019 – 2022（主持）

3. 中央高校基本科研业务费 2025-2026（主持）

4. 南京农业大学高层次引进人才启动基金（主持）

二. 代表性学术论文

[1] You Wu; Wenna Shao; Mengxiao Yan; Yuqin Wang; Pengfei Xu; Guoqiang Huang; Xiaofei Li; Brian D. Gregory; Jun Yang*; Hongxia Wang*; Xiang Yu*; Transfer learning enables identification of multiple types of RNA modifications using nanopore direct RNA sequencing, Nature Communications, 2024, 15(1) (一作) (中科院一区，IF: 18.1)

[2] Xiang Li#, Yitian Fang#, You Wu*, Xiang Yu*; FungiGuard: Identification of Plant Antifungal Peptides with Artificial Intelligence, Genome Biology, 2026 (共通讯作者)(中科院一区，IF: 9.2)

[3] You Wu#; Pengfei Xu#; Liyuan Wang#; Shuai Liu; Yingnan Hou; Hui Lu; Peng Hu*; Xiaofei Li*; Xiang Yu*; scGO: interpretable deep neural network for cell status annotation and disease diagnosis, Briefings In Bioinformatics, 2025, 26(1) (第一作者) (中科院二区，IF: 7.3)

[4] You Wu#; Wenna Shao#; Shuai Liu#; Liyuan Wang; Pengfei Xu; Xingpeng Zhang; Haihan Song; Xiaofei Li; Jian Wang*; Xiang Yu*; Simultaneous profiling of ac4C and m5C modifications from nanopore direct RNA sequencing, International Journal of Biological Macromolecules, 2025 (第一作者) (中科院二区，IF:8.7)

[5] Tianyuan Zhang#, Jia Li#, Chao Tang#, You Wu#, et. al. Nanopore Direct RNA Sequencing and the Epitranscriptome: Advances in Mapping Native RNA Landscapes. iMeta, 2026 (共一第四) (中科院一区，IF:44.4)

[6] Pengfei Xu#; Qihui Wan#; Wenna Shao#; You Wu#; Feijie Wu; Xiaorong Li; Wenqing Ren; Yuke He; Shuxia Li; Xiang Yu; Orchestration of leaf curvature by the SBP transcription factor SPL10- REVOLUTA module in Arabidopsis, Journal of Integrative Plant Biology, 2025 (共一第四) (中科院一区，IF: 12.5)

[7] Sirui Zhu#, Yuanyuan Li#, You Wu, Yanan Shen, Ying Wang, Yujie Yan, Weijun Chen, Qiong Fu, Yirong Wang, Xiang Yu, Feng Yu*, The FERONIA-YUELAO module participates in translational control by modulating the abundance of tRNA fragments in Arabidopsis, Developmental Cell, 2023, 58(24): 2930-2946 (期刊论文) (中科院一区，IF:9.2)

[8] Liyuan Wang*, Xuewei Xiang, Guoyu Yin, Haidong Shu, You Wu, Han Chen, Ren Na, Mark Gijzen, Yingnan Hou*, Suomeng Dong*, Effector gene silencing coordinated by histone methylation and small RNAs enhances host adaptation in a plant pathogen, Nucleic Acids Research,2026 (期刊论文) (新锐一区，IF: 15)

[9] Pengfei Xu#, Yaobin Wang#, You Wu, Shuhua Huang, Xiang Yu*, Multi-layered RNA decay mechanisms underlie subgenome-biased homoeologous mRNA stability in salt-stressed allopolyploid Plants (The plant journal, in revision)

[10] Wenna Shao#, Xueqin Li#, You Wu, Yue Niu, Pengfei Xu, Huanjun Li, Yan Bao, Wanqi Liang, Heng Zhang*, Brian D. Gregory*, Xiang Yu*, DXO1-RNMT1 coordinates m7G capping and translational regulation to confer heat tolerance in Arabidopsis (The plant journal, under review)

[11] Dongke Zhou, You Wu, Xiang Li, Xiaoxiao Xie, Pengfei Xu*, Yingying Zhang*, Xiang Yu*, Rhythmic oscillation of EJC-marked RNA decay associated with m6A and polyA tail dynamics in response to diurnal cues in plants (New Phytologist, under review)

[12] Liyuan Wang, You Wu, Xiang Yu, Yingnan Hou*, The NAD⁺ capped epitranscriptome of the Oomycete pathogen Phytophthora infestans (mLife, in revision)

[13] Chenxu Feng, Xiang Gao, Yixuan Wang, Ge Wang, Jiangying Liu, Yiqin Shen, You Wu, Weiwei Zhu, Lu Zhao, Zongyan Chen, Haihan Song, Jianhua Hua, Xiang Yu, Yongchun Zhang, Donglei Sun*, Bone marrow-derived CX3CR1+Ly6Cint noncanonical myeloid cells are early drivers of colorectal cancer liver metastasis via CCR1 and CCR5 (Cell reports, in revision)